American Airlines flies from Heathrow for almost all of its UK operation: in 2025 the airport handled 15,838 of its flights, 98% of its British network. They were disrupted almost three times as often as the national average (1.6%), and there were more cancellations (442) than flights 3+ hours late (294).
American, United and Delta versus BA and Virgin
At the same Heathrow, the American carriers ran into disruption 2–3 times as often as the British ones. American Airlines came in at 4.6%, United Airlines at 3.4%, Delta at 3.0%; British Airways at 1.6%, Virgin Atlantic at 1.8%. The site counts the Heathrow – Charlotte route across all airlines: 2,189 flights and 5.7%.
Where UK261 applies and where it doesn't
The UK Civil Aviation Authority (CAA) lists American Airlines as a US airline. On departure from the UK, the UK261 rules cover any airline: the distance to the US is over 3,500 km, so that means £260 for a delay of 3–4 hours and £520 for longer. On a flight from the US to the UK, they only apply if the carrier is British or from the EU.